Introduction Idiopathic thrombocytopenic purpura, which is also called ITP, is an autoimmune disorder that causes very low platelet counts. An autoimmune disorder is one in which a person produces antibodies against his or her own tissues. What is going on in the body? Platelets, which are made by the bone marrow, are essential for blood clotting. In ITP, the body produces antibodies that attack the platelets and destroy them. Normally the body makes antibodies to fight infections. In ITP, the body for some reason makes antibodies against its own tissues, called autoantibodies. These autoantibodies act to destroy platelets. The result is a low platelet count, known as thrombocytopenia. The cause of ITP is unknown. But certain viral infections seem to cause some cases of ITP. This in turn creates antibodies that attack the platelets, which are then removed from the bloodstream. Normal platelet counts are between 150,000 and 450,000. People with ITP may have very l...
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