Hormones (living messenger)
. Hormones are chemical substances that our bodies use to regulate every
physiological process. They are secreted by one cell or organ and used
by another. They circulate in our blood from the secretory organ to the
target organ. They are regulated by complex feedback loops that keep
them balanced within specific ranges. They are necessary for growth,
reproduction, maintenance of homeostasis, metabolism and all other life
functions
Cellular Functions And Receptors
Hormones function by regulating processes within the individual cells in
our bodies. They do this by combining with receptors on the cell
membrane. The hormone fits into a specific receptor much the same way
a key fits into a lock. When the hormone combines with a receptor, it
causes or blocks some activity.
For example, when insulin combines with insulin receptors, glucose is carried into the cell, where it can be used for energy
Their Building Blocks
Hormones are made from other substances, primarily proteins and fats. There are three main types of hormones.
Amine-derived hormones are made from tryptophan and tyrosine, two amino acids. Catecholamines are amine-derived hormones.
Peptides are made from chains of amino acids. Insulin is a peptide hormone. Sometimes peptid chains have glucose molecules attached to them, and they are called glycoproteins. These are larger hormone molecules, such as follicle stimulating hormone.
Lipid or phospholipids are made from fatty acids. Steroids, including sex hormones, and prostaglandins are examples of lipid hormones
Peptides are made from chains of amino acids. Insulin is a peptide hormone. Sometimes peptid chains have glucose molecules attached to them, and they are called glycoproteins. These are larger hormone molecules, such as follicle stimulating hormone.
Lipid or phospholipids are made from fatty acids. Steroids, including sex hormones, and prostaglandins are examples of lipid hormones
Hormone Replacement Therapy
Because they are necessary for cellular function, inadequate levels of
any hormone can have serious effects. Many of the diseases of aging may
be due to problems with hormone production, transportation or
receptors. Replacing them when you are deficient is often necessary,
especially as people grow older. Many people take thyroid hormone or
other hormone replacements.
Reference
1-Shuster, Michèle (2014-03-14). Biology for a changing world, with physiology (Second ed.). New York, NY. ISBN 9781464151132. OCLC 884499940.
2- "Signal relay pathways". Khan Academy. Retrieved 2019-11-13.
3-Stuenkel CA, Davis SR, Gompel A, Lumsden MA, Murad MH, Pinkerton JV, Santen RJ (November 2015). "Treatment of Symptoms of the Menopause: An Endocrine Society Clinical Practice Guideline" (PDF). J. Clin. Endocrinol. Metab. 100 (11): 3975–4011. doi:10.1210/jc.2015-2236. PMID 26444994.
Santen
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